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Department : CLINICAL PATHOLOGY

Urine Bence Jones Proteins (Electrophoresis) is a specialized test used to detect free light chain proteins (kappa or lambda) in urine. These proteins, known as Bence Jones proteins, are produced in excess in certain plasma cell disorders.

This test is primarily used in the diagnosis and monitoring of multiple myeloma and other related conditions such as light chain disease and Waldenström’s macroglobulinemia. The electrophoresis technique helps identify and characterize these abnormal proteins.

A urine sample is analyzed using electrophoresis, a laboratory technique that separates proteins based on their electrical charge and size. The presence of abnormal light chains (Bence Jones proteins) is identified and may be further confirmed with additional tests.

This test is recommended for individuals with:

• Suspected multiple myeloma
• Bone pain or unexplained fractures
• Fatigue or weakness
• Recurrent infections
• Unexplained proteinuria
• Abnormal blood or urine test results