TPMT (THIOPURINE METHYL TRANSFERASE) GENOTYPING*

Test info :

The TPMT Genotyping test identifies genetic variations affecting thiopurine drug metabolism to guide safe medication use.

Preparation Required :

Consult your doctor. No fasting is usually required Inform your doctor about current medications Genetic counseling may be recommended Follow any specific instructions given by your healthcare provider

Total Price

₹7,375.00

Free home collection available depending on the package type. Reports delivered online to your email and phone number.

Tests Details :

Home Collection

Department : IMMUNOLOGY

The TPMT (Thiopurine Methyl Transferase) Genotyping test is a genetic test used to detect variations in the TPMT gene, which influences how the body metabolizes thiopurine medications such as azathioprine, mercaptopurine, and thioguanine.

Individuals with reduced or absent TPMT enzyme activity are at higher risk of severe drug toxicity, including bone marrow suppression, when treated with standard doses of these medications.

This test helps clinicians personalize treatment by adjusting drug dosage or selecting alternative therapies, improving safety and effectiveness. It is commonly performed before initiating thiopurine therapy in conditions such as autoimmune diseases, organ transplantation, and certain cancers.