Lab test · Immunology
TPMT (Thiopurine Methyl Transferase) Genotyping
The TPMT Genotyping test identifies genetic variations affecting thiopurine drug metabolism to guide safe medication use.The TPMT Genotyping test identifies genetic variations affecting thiopurine drug metabolism to guide safe medication use.
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Free home collection Report in 24 hrs
ReportWithin 24 hrs
SampleBlood
CollectionHome or centre
FastingNot needed
How it works
1
Book in a minute
Add to cart, pick a date and time slot, pay online or at collection.
2
Sample collected at home or centre
A trained phlebotomist arrives in your slot with sealed, single-use kits.
3
Report on WhatsApp
Within 24 hours on WhatsApp and under My Orders.
Preparation
No special preparation needed unless your doctor advises otherwise.
About this test
The TPMT Genotyping test identifies genetic variations affecting thiopurine drug metabolism to guide safe medication use.
The TPMT (Thiopurine Methyl Transferase) Genotyping test is a genetic test used to detect variations in the TPMT gene, which influences how the body metabolizes thiopurine medications such as azathioprine, mercaptopurine, and thioguanine.
Individuals with reduced or absent TPMT enzyme activity are at higher risk of severe drug toxicity, including bone marrow suppression, when treated with standard doses of these medications.
This test helps clinicians personalize treatment by adjusting drug dosage or selecting alternative therapies, improving safety and effectiveness. It is commonly performed before initiating thiopurine therapy in conditions such as autoimmune diseases, organ transplantation, and certain cancers.
Test Recommended For
- Patients before starting thiopurine medications
- Individuals with autoimmune disorders
- Organ transplant recipients
- Patients undergoing chemotherapy
- Individuals advised for pharmacogenetic testing
What patients say about Prima
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Questions people ask
How soon will I get my report?
Your report is delivered within 24 hours of sample collection — on WhatsApp and under My Orders.
Is home sample collection available?
Yes. A trained phlebotomist visits your home with sealed, single-use kits. Home collection is free.
Do I need to fast or prepare?
No fasting is required for this test unless your doctor advises otherwise.
How do I pay?
Pay online (UPI / cards) or pay at collection or at the centre. The price you see is what you pay — it includes the report, with no hidden charges.
Is the lab accredited?
Yes. Prima Diagnostics runs NABL-certified labs with strict quality control across 7 centres in Bengaluru.
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