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Department : IMMUNOLOGY

The MuSK (Muscle-Specific Kinase) Antibody test is a blood test used to detect antibodies against muscle-specific kinase, a protein involved in communication between nerves and muscles.

These antibodies are commonly associated with a subtype of myasthenia gravis, an autoimmune disorder that causes muscle weakness and fatigue. The test is particularly useful in patients who are negative for acetylcholine receptor (AChR) antibodies but still show symptoms of myasthenia gravis.

This test is recommended for individuals who have:

• Muscle weakness that worsens with activity
• Drooping eyelids (ptosis) or double vision
• Difficulty in speaking, chewing, or swallowing
• Suspected myasthenia gravis
• Negative AChR antibody test but persistent symptoms

Doctors may recommend this test for further evaluation of neuromuscular conditions.