HSV II Antibody IgG

This Test is a blood test that detects Immunoglobulin G (IgG) antibodies produced in response to Herpes Simplex Virus type 2 (HSV-2) infection.

HSV-2 is primarily associated with genital herpes, a sexually transmitted infection that can cause sores, blisters, and discomfort in the genital area. The presence of IgG antibodies indicates past exposure or an established infection, as these antibodies develop after the initial infection and remain in the body long-term.

The purpose of this test is to:

• Detect IgG antibodies against HSV-2
• Identify past or long-term HSV-2 infection
• Support diagnosis in individuals with recurrent genital herpes
• Assist in overall evaluation of herpes infection status

HSV II ANTIBODY IGG Test

The HSV II Antibody IgG test detects IgG antibodies against Herpes Simplex Virus Type 2 (HSV-2) in the blood. HSV-2 is most commonly associated with genital herpes, although symptoms and infection patterns can vary between individuals.

IgG antibodies generally develop after exposure to HSV and can remain detectable for a long period. Therefore, a positive HSV-2 IgG result generally indicates previous or established exposure to HSV-2. However, the test cannot determine exactly when the infection occurred or whether the virus is currently active.

If active genital sores, blisters, or ulcers are present, a healthcare provider may recommend HSV PCR/NAAT testing from a lesion, which is more useful for confirming the presence of the virus during an outbreak.

This Test is Recommended for Individuals:

• Individuals with symptoms suggestive of genital herpes
• People with recurrent genital sores, blisters, or ulcers
• Individuals whose sexual partner has known HSV-2 infection, when testing is clinically appropriate
• People being evaluated for possible sexually transmitted infections (STIs)
• Individuals who need assessment of previous HSV-2 exposure based on their clinical history
• Pregnant individuals when HSV testing is specifically recommended by their healthcare provider

FAQs

1. What does a positive HSV-2 IgG result mean?
A positive HSV-2 IgG result generally indicates that HSV-2 antibodies are present, suggesting previous or established exposure to HSV-2. It does not necessarily mean that an active outbreak is occurring.

2. Can HSV-2 IgG tell me when I became infected?
No. HSV-2 IgG cannot determine the exact timing of infection. A positive result may reflect an infection acquired in the past.

3. Is HSV-2 IgG able to detect an active herpes outbreak?
No. The IgG test detects antibodies rather than the virus itself. If active lesions are present, PCR/NAAT testing from the lesion may be more appropriate for detecting an active HSV infection.