The Smith Antibody (Anti-Sm) test is a blood test used to detect antibodies directed against Smith (Sm) nuclear antigens. These antibodies are highly specific for systemic lupus erythematosus (SLE), an autoimmune disease affecting multiple organs.
Although Anti-Sm antibodies are not present in all patients with lupus, their presence strongly supports the diagnosis.
Detection of Anti-Sm antibodies helps in confirming diagnosis and evaluating autoimmune activity, aiding in appropriate clinical management.
The purpose of this test is to