Smear for Tzank Stain

The Smear for Tzanck Stain is a microscopic test used to examine cells collected from skin lesions, blisters, or ulcers. The sample is stained and observed under a microscope to identify characteristic cellular changes.

This test is commonly used to detect viral infections such as herpes simplex virus (HSV) and varicella-zoster virus (VZV). It can also help in diagnosing certain blistering skin conditions by identifying multinucleated giant cells.

Although it provides rapid preliminary results, further confirmatory tests such as viral culture or PCR may be required for definitive diagnosis.

The purpose of this test is to

• To detect viral infections like herpes
• To examine cellular changes in skin lesions
• To support diagnosis of blistering disorders
• To provide rapid preliminary diagnosis
• To guide further testing