Prothrombin Gene Mutation Analysis
The Prothrombin Gene Mutation Analysis test detects genetic mutations associated with increased risk of abnormal blood clot formation.
The Prothrombin Gene Mutation Analysis test is a genetic test used to identify mutations in the prothrombin (Factor II) gene, most commonly the G20210A mutation. This mutation can increase the tendency of blood to clot, leading to a higher risk of thrombosis.
Individuals with this mutation may be at increased risk for conditions such as deep vein thrombosis (DVT) and pulmonary embolism. The test is particularly useful in evaluating individuals with unexplained blood clots or a family history of clotting disorders.
This test is often performed along with other thrombophilia screening tests to assess inherited clotting risks and guide appropriate medical management.
The purpose of this test is to
- To detect prothrombin gene mutations
- To assess risk of inherited thrombophilia
- To evaluate unexplained blood clots
- To support diagnosis of clotting disorders
- To guide preventive and treatment strategies