PLA2 Receptor Antidoby

The PLA2 Receptor Antibody test is a blood test used to detect antibodies against the phospholipase A2 (PLA2) receptor found on kidney cells. These antibodies are strongly associated with primary membranous nephropathy, an autoimmune condition affecting the kidneys.

This condition leads to damage of the kidney’s filtering units (glomeruli), resulting in protein loss in urine (proteinuria), swelling, and potential kidney dysfunction. The presence of PLA2 receptor antibodies helps in confirming the diagnosis and distinguishing primary membranous nephropathy from secondary causes.

The purpose of this test is to

• To detect PLA2 receptor antibodies in the blood
• To diagnose primary membranous nephropathy
• To differentiate primary from secondary kidney disease
• To assess autoimmune activity affecting the kidneys
• To monitor disease progression and treatment response