Parietal Cell and Intrinsic Factor Antibody (1:10 Dilution of Serum)
The Parietal Cell and Intrinsic Factor Antibody test detects antibodies associated with autoimmune gastric disorders and vitamin B12 deficiency.
The Parietal Cell and Intrinsic Factor Antibody test is a blood test used to detect autoantibodies against gastric parietal cells and intrinsic factor. These antibodies are commonly associated with autoimmune conditions affecting the stomach lining.
Parietal cells are responsible for producing stomach acid and intrinsic factor, which is essential for vitamin B12 absorption. The presence of these antibodies may lead to conditions such as pernicious anemia and chronic atrophic gastritis.
This test is often recommended in patients with suspected vitamin B12 deficiency, anemia, or unexplained neurological symptoms. It helps in diagnosing autoimmune causes of impaired vitamin B12 absorption and guides appropriate treatment.
The purpose of this test is to
- To detect parietal cell and intrinsic factor antibodies
- To diagnose autoimmune gastric disorders
- To help identify pernicious anemia
- To evaluate causes of vitamin B12 deficiency
- To support assessment of stomach-related autoimmune conditions