Lab test · Biochemistry
Osmotic Fragility Test
The Osmotic Fragility Test measures the resistance of red blood cells to hemolysis in varying saline concentrations, helping diagnose hereditary sphe…The Osmotic Fragility Test measures the resistance of red blood cells to hemolysis in varying saline concentrations, helping diagnose hereditary spherocytosis and other red cell disorders.
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FastingNot needed
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Report on WhatsApp
Within 24 hours on WhatsApp and under My Orders.
Preparation
No special preparation needed unless your doctor advises otherwise.
About this test
The Osmotic Fragility Test measures the resistance of red blood cells to hemolysis in varying saline concentrations, helping diagnose hereditary spherocytosis and other red cell disorders.
The Osmotic Fragility Test is a diagnostic blood test used to evaluate the stability and integrity of red blood cells (RBCs) when exposed to different concentrations of saline solution. It measures how easily RBCs rupture (hemolyze) under osmotic stress.
This test is particularly useful in diagnosing hereditary spherocytosis, a condition where red blood cells are more fragile and prone to destruction. It may also be used to assess other hemolytic anemias and red cell membrane disorders.
The purpose of the Osmotic Fragility Test is to
- To assess the fragility of red blood cells
- To diagnose hereditary spherocytosis
- To evaluate hemolytic anemia
- To detect red blood cell membrane disorders
- To support investigation of abnormal RBC destruction
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Is home sample collection available?
Yes. A trained phlebotomist visits your home with sealed, single-use kits. Home collection is free.
Do I need to fast or prepare?
No fasting is required for this test unless your doctor advises otherwise.
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