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Department : IMMUNOLOGY

The Methotrexate Level test is a blood test used to measure the concentration of methotrexate, a medication commonly used in cancer treatment, autoimmune diseases, and certain inflammatory conditions.

Monitoring methotrexate levels is crucial, especially in high-dose therapy, to ensure that the drug is within a safe and effective range. Elevated levels may lead to toxicity affecting the liver, kidneys, and bone marrow.

This test helps doctors adjust dosage, monitor drug clearance, and guide supportive treatments such as leucovorin rescue therapy to minimize side effects.

This test is recommended for individuals who:

• Are receiving methotrexate therapy (especially high-dose)
• Are undergoing cancer treatment
• Have autoimmune conditions like rheumatoid arthritis
• Require monitoring for drug toxicity
• Need dose adjustment based on drug levels

Doctors use this test to ensure safe and effective treatment.