HEPATITIS C VIRUS ANTIBODY (ANTI-HCV), IGM & IGG Test

The Hepatitis C Virus Antibody (Anti-HCV), IgM & IgG test detects antibodies produced by the immune system in response to hepatitis C virus (HCV) infection.

Testing for HCV antibodies can help identify whether an individual has been exposed to hepatitis C. However, the presence of antibodies does not by itself confirm an active infection because antibodies can remain detectable even after the virus has been cleared or successfully treated.

Anti-HCV testing may be used during screening or when hepatitis C infection is suspected. If antibodies are detected, an HCV RNA test (PCR/NAT) is generally needed to determine whether the virus is currently present in the blood.

Test Recommended for Individuals:

• Individuals undergoing hepatitis C screening
• People with a known or suspected exposure to HCV
• Individuals with risk factors for hepatitis C infection
• People with unexplained elevation of liver enzymes
• Individuals with symptoms or clinical findings suggestive of viral hepatitis
• People with a previous history of hepatitis C exposure
• Patients advised by their healthcare provider to undergo HCV testing

FAQs

1. What does a positive Anti-HCV IgM & IgG result mean?
A positive result indicates that antibodies against HCV have been detected, suggesting previous or current exposure to hepatitis C. It does not, by itself, confirm an active infection.

2. What is the difference between HCV IgM and IgG antibodies?
IgM and IgG are different types of antibodies produced by the immune system. However, HCV antibody testing is not generally used to reliably distinguish acute from chronic hepatitis C based solely on IgM versus IgG. HCV RNA testing is more useful for confirming active infection.

3. What test is needed after a positive Anti-HCV result?
If HCV antibodies are detected, an HCV RNA test is generally recommended to determine whether there is an active hepatitis C infection. Your healthcare provider may also recommend liver function tests and other assessments based on your clinical situation.