The Quadruple Marker test is a maternal blood screening test typically performed during the second trimester of pregnancy (usually between 15 to 20 weeks). It measures four substances in the mother’s blood: Alpha-fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Estriol (uE3), and Inhibin A.
These markers help assess the risk of chromosomal abnormalities such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and neural tube defects in the developing fetus.
This test does not provide a definitive diagnosis but indicates the likelihood of certain conditions.
The purpose of this test is to